Active Ingredient

 





Cannabinoids .... 

1940’s


            These are all patents by Roger Adams

Isolation of cannabidiol

https://patents.google.com/patent/US2304669A/en - 1940

Marihuana active compounds

https://patents.google.com/patent/US2419935A - 1941

Optically active tetrahydrodibenzopyrans having marihuana activity and process for making same

https://patents.google.com/patent/US2419934A - 1941

Preparation of compounds with marihuana activity

https://patents.google.com/patent/US2419936A - 1942

Marihuana active compounds

https://patents.google.com/patent/US2419937A/ - 1944


 

 

Periodical articles.... 

Structure of Cannabidiol,
A Product Isolated from the Marihuana Extract of Minnesota Wild Hemp
Roger Adams, Madison Hunt, and J. H. Clark
https://pubs.acs.org/doi/10.1021/ja01858a058
J. Am. Chem. Soc. 1940, 62, 1, 196–200
Publication Date:January 1, 1940
https://doi.org/10.1021/ja01858a058

Adams R. Marihuana: Harvey Lecture, February 19, 1942. Bull N Y Acad Med. 1942Nov;18(11):705-30. PMID: 19312292; PMCID: PMC1933888.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933888/

Isolation of a Physiologically Active Tetrahydrocannabinol from Cannabis Sativa Resin
H. J. Wollner, John R. Matchett, Joseph Levine, and S. Loewe
https://pubs.acs.org/doi/abs/10.1021/ja01253a008
J. Am. Chem. Soc. 1942, 64, 1, 26–29
Publication Date:January 1, 1942
https://doi.org/10.1021/ja01253a008




1960’s 

 

A Total Synthesis of dl-Δ1-Tetrahydrocannabinol, the Active Constituent of Hashish1
R. Mechoulam,  and Y. Gaoni
https://pubs.acs.org/doi/abs/10.1021/ja01092a065
J. Am. Chem. Soc. 1965, 87, 14, 3273–3275
Publication Date:July 1, 1965
https://doi.org/10.1021/ja01092a065


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